N,N-dimethyltryptamine(DMT) is a psychoactive chemical in the tryptamine family, which causes intense visuals and strong psychedelic mental affects when smoked, injected, snorted, or when swallowed orally (with an MAOI such as haramaline). DMT was first synthesized in 1931, and demonstrated to be hallucinogenic in 1956. It has been shown to be present in many plant genera (Acacia, Anadenanthera, Mimosa, Piptadenia, Virola) and is a major component of several hallucinogenic snuffs (cohoba, parica, yopo). It is also present in the intoxicating beverage ayahuasca made from banisteriopsis caapi. This drink inspired much rock art and paintings drawn on the walls of native shelters in tribal Africa- what would be called 'psychedelic' art today (Bindal, 1983). The mechanism of action of DMT and related compounds is still a scientific mystery, however DMT has been identified as an endogenous psychadelic- it is a neurotransmitter found naturally in the human body and takes part in normal brain metabolism. Twenty-five years ago, Japanese scientists discovered that the brain actively transports DMT across the blood-brain barrier into its tissues. "I know of no other psychedelic drug that the brain treats with such eagerness," said one of the scientists. What intrigued me were the questions, how and why does DMT alter our perception so drastically if it is already present in our bodies?
DMT is known as the "spirit molecule" because it elicits with reasonable reliability, certain psychological states that are considered 'spiritual.' These are feelings of extraordinary joy, timelessness, and a certainty that what we are experiencing is more real than present day reality. DMT leads us to an acceptance of the coexistence of opposites, such as life and death, good and evil; a knowledge that consciousness continues after death; a deep understanding of the basic unity of all phenomena; and a sense of wisdom or love pervading all existence. The smoked DMT experience is short, but generally incredibly intense. Onset is fast and furious, and thus the term "mind-blowing" was used to describe the effect. It is a fully engaging and enveloping experience of visions and visuals, which vary greatly from one individual to the next. Users report visiting other worlds, talking with alien entities, profound changes in ontological perspective, fanciful dreamscapes, frightening and overwhelming forces, complete shifts in perception and identity followed by an abrupt return to baseline. "The effect can be like instant transportation to another universe for a timeless sojourn" (Alan Watts).